Noah Webster's Dictionary 1. (n.) Deprivation of advantage; unfavorable or prejudicial quality, condition, circumstance, or the like; that which hinders success, or causes loss or injury. 2. (n.) Loss; detriment; hindrance; prejudice to interest, fame, credit, profit, or other good. 3. (v. t.) To injure the interest of; to be detrimental to.

Multi-Version Concordance Disadvantage (1 Occurrence) Acts 28:21 "For our part," they replied, "we have not received any letters from Judaea about you, nor have any of our countrymen come here and reported or stated anything to your disadvantage. (WEY)